Plant, Darren : rechercher sur Z-Library

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1

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Clare, Rachel H., Bardelle, Catherine, Harper, Paul, Hong, W. David, Börjesson, Ulf, Johnston, Kelly L., Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Co

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2019

2

Genetics and epigenetics of rheumatoid arthritis

Viatte, Sebastien, Plant, Darren, Raychaudhuri, Soumya

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Année:

2013

Langue:

english

Fichier:

PDF, 703 KB

english, 2013

3

Genetic and genomic predictors of anti-TNF response

Prajapati, Rita, Plant, Darren, Barton, Anne

Journal:

Pharmacogenomics

Année:

2011

Langue:

english

Fichier:

PDF, 761 KB

english, 2011

4

Assessing the Role of DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio in Rheumatoid Arthritis

Ambatipudi, Srikant, Sharp, Gemma C., Clarke, Sarah L. N., Plant, Darren, Tobias, Jonathan H., Evans, David M., Barton, Anne, Relton, Caroline L.

Journal:

Journal of Immunology Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2018

5

Machine learning in precision medicine: lessons to learn

Plant, Darren, Barton, Anne

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Année:

2020

Fichier:

PDF, 552 KB

2020

6

Benefit of early treatment in inflammatory polyarthritis patients with anti–cyclic citrullinated peptide antibodies versus those without antibodies

Tracey M. Farragher, Mark Lunt, Darren Plant, Diane K. Bunn, Anne Barton, Deborah P. M. Symmons

Journal:

Arthritis Care & Research

Année:

2010

Langue:

english

Fichier:

PDF, 107 KB

english, 2010

7

Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients

Tracey M. Farragher, Darren Plant, Edward Flynn, Steve Eyre, Diane Bunn, Wendy Thomson, Deborah Symmons, Anne Barton

Journal:

Arthritis Care & Research

Année:

2010

Langue:

english

Fichier:

PDF, 81 KB

english, 2010

8

Genome-wide association study of genetic predictors of anti–tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci

Darren Plant, John Bowes, Catherine Potter, Kimme L. Hyrich, Ann W. Morgan, Anthony G. Wilson, John D. Isaacs, Wellcome Trust Case Control Consortium, British Society for Rheumatology Biologics Regist

Journal:

Arthritis & Rheumatism

Année:

2011

Langue:

english

Fichier:

PDF, 85 KB

english, 2011

9

Replication of association of the PTPRC gene with response to anti–tumor necrosis factor therapy in a large UK cohort

Darren Plant, Rita Prajapati, Kimme L. Hyrich, Ann W. Morgan, Anthony G. Wilson, John D. Isaacs, Biologics in Rheumatoid Arthritis Genetics, Genomics Study Syndicate, Anne Barton

Journal:

Arthritis & Rheumatism

Année:

2012

Langue:

english

Fichier:

PDF, 77 KB

english, 2012

10

Macrophage Migration Inhibitory Factor Gene Polymorphism is Associated with Psoriasis

Donn, Rachelle P., Plant, Darren, Jury, Francine, Richards, Helen L., Worthington, Jane, Ray, David W., Griffiths, Christopher E. M.

Journal:

The Journal of Investigative Dermatology

Année:

2004

Langue:

english

Fichier:

PDF, 77 KB

english, 2004

11

The CX3CL1–CX3CR1 system and psoriasis

Darren Plant, Helen S. Young, Rachel E. B. Watson, Jane Worthington, Christopher E. M. Griffiths

Journal:

Experimental Dermatology

Année:

2006

Langue:

english

Fichier:

PDF, 80 KB

english, 2006

12

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13

Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Plant, Darren, Gibbons, Laura J, Wilson, Anthony G, Bax, Deborah E

Journal:

Nature Genetics

Année:

2008

Langue:

english

Fichier:

PDF, 120 KB

english, 2008

13

Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

Mahdi, Hiba, Fisher, Benjamin A, Källberg, Henrik, Plant, Darren, Malmström, Vivianne, Rönnelid, Johan, Charles, Peter, Ding, Bo, Alfredsson, Lars, Padyukov, Leonid

Journal:

Nature Genetics

Année:

2009

Langue:

english

Fichier:

PDF, 562 KB

english, 2009

14

Interaction between Genetic Control of Vascular Endothelial Growth Factor Production and Retinoid Responsiveness in Psoriasis

Young, Helen S, Summers, Angela M, Read, Ian R, Fairhurst, David A, Plant, Darren J, Campalani, Emanuela, Smith, Catherine H, Barker, Jonathan N W N, Detmar, Michael J, Brenchley, Paul E C

Journal:

The Journal of Investigative Dermatology

Année:

2005

Langue:

english

Fichier:

PDF, 116 KB

english, 2005

15

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

Darren Plant, Ibrahim Ibrahim, Mark Lunt, Stephen Eyre, Edward Flynn, Kimme L Hyrich, Ann W Morgan, Anthony G Wilson, John D Isaacs, Anne Barton

Journal:

Arthritis Research & Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 170 KB

english, 2012

16

Genetic and epigenetic predictors of responsiveness to treatment in RA

Plant, Darren, Wilson, Anthony G., Barton, Anne

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Année:

2014

Langue:

english

Fichier:

PDF, 720 KB

english, 2014

17

Effect of inadequate adherence on clinical outcomes: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

Bluett, James, Morgan, Catharine, Thurston, Layla, Plant, Darren, Morgan, Ann, Wilson, Anthony, Isaacs, John, Hyrich, Kimme, Cordingley, Lis, Barton, Anne

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 54 KB

english, 2014

18

Impact of Psychological Factors on Subjective Disease Activity Assessments in Patients With Severe Rheumatoid Arthritis

Cordingley, Lis, Prajapati, Rita, Plant, Darren, Maskell, Deborah, Morgan, Catharine, Ali, Faisal R., Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Barton, Anne

Journal:

Arthritis Care & Research

Année:

2014

Langue:

english

Fichier:

PDF, 122 KB

english, 2014

19

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis

Jani, Meghna, Chinoy, Hector, Warren, Richard B, Griffiths, Christopher E M, Plant, Darren, Morgan, Ann W, Wilson, Anthony G, Hyrich, Kimme L, Isaacs, John, Barton, Anne

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 62 KB

english, 2015

20

Association of HLA-DRB1 Haplotypes With Rheumatoid Arthritis Severity, Mortality, and Treatment Response

Viatte, Sebastien, Plant, Darren, Han, Buhm, Fu, Bo, Yarwood, Annie, Thomson, Wendy, Symmons, Deborah P. M., Worthington, Jane, Young, Adam, Hyrich, Kimme L., Morgan, Ann W., Wilson, Anthony G., Isaac

Journal:

JAMA The Journal of the American Medical Association

Année:

2015

Langue:

english

Fichier:

PDF, 498 KB

english, 2015

21

Genetic and genomic markers of anti-TNF treatment response in rheumatoid arthritis

Oliver, James, Plant, Darren, Webster, Amy P, Barton, Anne

Journal:

Biomarkers in Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2015

22

Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register: Table 1

Ibrahim, Ibrahim, Humphreys, Jennifer, Mokhtar, Ibtisam, Marshall, Tarnya, Verstappen, Suzanne, Symmons, Deborah, Viatte, Sebastien, Barton, Anne, Plant, Darren

Journal:

Annals of the Rheumatic Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 144 KB

english, 2015

23

Clinical Utility of Random Anti-Tumor Necrosis Factor Drug-Level Testing and Measurement of Antidrug Antibodies on the Long-Term Treatment Response in Rheumatoid Arthritis

Jani, Meghna, Chinoy, Hector, Warren, Richard B., Griffiths, Christopher E. M., Plant, Darren, Fu, Bo, Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Hyrich, KimmeL., Barton, Anne

Journal:

Arthritis & Rheumatology

Année:

2015

Langue:

english

Fichier:

PDF, 97 KB

english, 2015

24

InvestigatingCD11cexpression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples

Smith, Samantha Louise, Eyre, Stephen, Yarwood, Annie, Hyrich, Kimme, Morgan, Ann W., Wilson, A. G., Isaacs, John, Plant, Darren, Barton, Anne

Journal:

Arthritis Research & Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 624 KB

english, 2015

25

Previously reported PDE3A–SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort

Smith, Samantha Louise, Plant, Darren, Lee, Xiu Hue, Massey, Jonathan, Hyrich, Kimme, Morgan, Ann W, Wilson, Anthony G, Isaacs, John, Barton, Anne

Journal:

Pharmacogenomics

Année:

2016

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2016

26

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients

Bowes, John D., Potter, Catherine, Gibbons, Laura J., Hyrich, Kimme, Plant, Darren, Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Worthington, Jane, Barton, Anne

Journal:

Pharmacogenetics and Genomics

Année:

2009

Langue:

english

Fichier:

PDF, 84 KB

english, 2009

27

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis

Plant, Darren, Webster, Amy, Nair, Nisha, Oliver, James, Smith, Samantha L., Eyre, Steven, Hyrich, Kimme L., Wilson, Anthony G., Morgan, Ann W., Isaacs, John D., Worthington, Jane, Barton, Anne

Journal:

Arthritis & Rheumatology

Année:

2016

Langue:

english

Fichier:

PDF, 341 KB

english, 2016

28

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels

Jani, Meghna, Isaacs, John D., Morgan, Ann W., Wilson, Anthony G., Plant, Darren, Hyrich, Kimme L., Chinoy, Hector, Barton, Anne

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 132 KB

english, 2016

29

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort

Jani, Meghna, Isaacs, John D, Morgan, Ann W, Wilson, Anthony G, Plant, Darren, Hyrich, Kimme L, Chinoy, Hector, Barton, Anne

Journal:

Annals of the Rheumatic Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 502 KB

english, 2017

30

HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study

Bluett, James, Owen, Sally-Ann, Massey, Jonathan, Alfirevic, Ana, Pirmohamed, Munir, Plant, Darren, Verstappen, Suzanne M M, Barton, Anne

Journal:

Annals of the Rheumatic Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 452 KB

english, 2017

31

Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis

Wei, Wen-Hua, Bowes, John, Plant, Darren, Viatte, Sebastien, Yarwood, Annie, Massey, Jonathan, Worthington, Jane, Eyre, Stephen

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 782 KB

english, 2016

32

GENETICS258. INVESTIGATION OF DIFFERENTIAL METHYLATION AS A POTENTIAL BIOMARKER OF METHOTREXATE RESPONSE IN PATIENTS WITH RHEUMATOID ARTHRITIS

Nair, Nisha, Plant, Darren, Verstappen, Suzanne M., Isaacs, John D., Morgan, Ann W., Hyrich, Kimme L., Barton, Anne, Wilson, Anthony G.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 42 KB

english, 2017

33

248 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis

Massey, Jonathan, Plant, Darren, Hyrich, Kimme, Morgan, Ann W, Wilson, Anthony G, Spiliopoulou, Athina, Colombo, Marco, McKeigue, Paul, Isaacs, John, Pitzalis, Costantino, Barton, Anne

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 42 KB

english, 2018

34

231 Pre-treatment anxiety and depression levels are correlated with less improvement in self-reported disease activity in rheumatoid arthritis patients treated with biological therapy: results from the BRAGGSS cohort

Dyball, Sarah, Cordingley, Lis, Isaacs, John D, Wilson, Gerry, Morgan, Ann, Hyrich, Kimme, Plant, Darren, Barton, Anne

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 30 KB

english, 2018

35

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

Taylor, John C., Bongartz, Tim, Massey, Jonathan, Mifsud, Borbala, Spiliopoulou, Athina, Scott, Ian C., Wang, Jianmei, Morgan, Michael, Plant, Darren, Colombo, Marco, Orchard, Peter, Twigg, Sarah, McI

Journal:

The Pharmacogenomics Journal

Année:

2018

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2018

36

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort

Smith, Samantha Louise, Plant, Darren, Eyre, Stephen, Hyrich, Kimme, Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Barton, Anne

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 181 KB

english, 2017

37

Identification of the Tyrosine-Protein Phosphatase Non-Receptor Type 2 as a Rheumatoid Arthritis Susceptibility Locus in Europeans

Cobb, Joanna E., Plant, Darren, Flynn, Edward, Tadjeddine, Meriem, Dieudé, Philippe, Cornélis, François, Ärlestig, Lisbeth, Dahlqvist, Solbritt Rantapää, Goulielmos, George, Boumpas, Dimitrios T., Sid

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 101 KB

english, 2013

38

Lack of Association of Variants Previously Associated with Anti-TNF Medication Response in Rheumatoid Arthritis Patients: Results from a Homogeneous Greek Population

Zervou, Maria I., Myrthianou, Efsevia, Flouri, Irene, Plant, Darren, Chlouverakis, Gregory, Castro-Giner, Francesc, Rapsomaniki, Panayiota, Barton, Anne, Boumpas, Dimitrios T., Sidiropoulos, Prodromos

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 229 KB

english, 2013

39

Tissue and Bronchoalveolar Lavage Biomarkers in Idiopathic Pulmonary Fibrosis Patients on Pirfenidone

Ronan, Nicola, Bennett, Deirdre M., Khan, Kashif A., McCarthy, Yvonne, Dahly, Darren, Bourke, Louise, Chelliah, Adeline, Cavazza, Alberto, O’Regan, Kevin, Moloney, Fiachra, Plant, Barry J., Henry, Mic

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2018

40

Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis

Massey, Jonathan, Plant, Darren, Hyrich, Kimme, Morgan, Ann W., Wilson, Anthony G., Spiliopoulou, Athina, Colombo, Marco, McKeigue, Paul, Isaacs, John, Cordell, Heather, Pitzalis, Costantino, Barton,

Journal:

The Pharmacogenomics Journal

Année:

2018

Langue:

english

Fichier:

PDF, 476 KB

english, 2018

41

Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins

Webster, Amy P., Plant, Darren, Ecker, Simone, Zufferey, Flore, Bell, Jordana T., Feber, Andrew, Paul, Dirk S., Beck, Stephan, Barton, Anne, Williams, Frances M. K., Worthington, Jane

Journal:

Genome Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2018

42

Gene expression profiling identifies classifier of methotrexate non-response in patients with rheumatoid arthritis

Plant, Darren, Maciejewski, Mateusz, Smith, Samantha, Nair, Nisha, Hyrich, Kimme, Ziemek, Daniel, Barton, Anne, Verstappen, Suzanne

Journal:

Arthritis & Rheumatology

Année:

2019

Langue:

english

Fichier:

PDF, 567 KB

english, 2019

43

Prediction of treatment response in rheumatoid arthritis patients using genome‐wide SNP data

Cherlin, Svetlana, Plant, Darren, Taylor, John C., Colombo, Marco, Spiliopoulou, Athina, Tzanis, Evan, Morgan, Ann W., Barnes, Michael R., McKeigue, Paul, Barrett, Jennifer H., Pitzalis, Costantino, B

Journal:

Genetic Epidemiology

Année:

2018

Langue:

english

Fichier:

PDF, 830 KB

english, 2018

44

055 Can interleukin IL-17A levels predict response to biologic treatment in patients with rheumatoid arthritis?

McDonald, Stephen, Reed, Rachel, Baricevic-Jones, Ivona, Ling, Stephanie, Plant, Darren, Barton, Anne

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 65 KB

english, 2019

45

Development of a High-Throughput Cytometric Screen to Identify Anti- Wolbachia Compounds: The Power of Public–Private Partnership

Clare, Rachel H., Clark, Roger, Bardelle, Catherine, Harper, Paul, Collier, Matthew, Johnston, Kelly L., Plant, Helen, Plant, Darren, McCall, Eileen, Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Ford,

Journal:

Année:

2019

Fichier:

PDF, 545 KB

2019

46

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kim

Journal:

Annals of the Rheumatic Diseases

Année:

2019

Langue:

english

Fichier:

PDF, 468 KB

english, 2019

47

055 Can interleukin IL-17A levels predict response to biologic treatment in patients with rheumatoid arthritis?

McDonald, Stephen, Reed, Rachel, Baricevic-Jones, Ivona, Ling, Stephanie, Plant, Darren, Barton, Anne

Journal:

Année:

2019

Fichier:

PDF, 65 KB

2019

48

Adding value to real-world data: the role of biomarkers

Plant, Darren, Barton, Anne

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 229 KB

english, 2019

49

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kim

Journal:

Annals of the Rheumatic Diseases

Année:

2019

Fichier:

PDF, 468 KB

2019

50

Adding value to real-world data: the role of biomarkers

Plant, Darren, Barton, Anne

Journal:

Année:

2019

Fichier:

PDF, 229 KB

2019